• Psychedelics - assisted therapy in


    Despite the huge therapeutic potential, psychedelic-assisted psychotherapy is not part of standard medical care yet. Self-medicating with psychedelics can produce undesired results, but despite that, more and more people feel disappointed with the efficacy of the current treatments and they turn to risky, but potentially more beneficial psychedelic-assisted therapy. The goal of this guide is harm reduction for people, who decided to self-medicate, we don’t encourage possession or consumption of illicit substances even for therapeutic endeavours.

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Legal status of psychedelics in Colorado

Colorado has made personal drug possession a misdemeanor crime in order to reduce incarceration rates. A new law went into effect in Colorado on March 1, 2020, allowing possession of 4 grams or less of most Schedule 1 and 2 substances a misdemeanor rather than a felony crime. Possession of certain “date rape” substances, however, will remain a level 4 drug offense under the new legislation. The law’s aim is to limit imprisonment for drug users who are found with cocaine or heroin. Schedule 1 drugs thought to “have a high risk of misuse and addiction”, and even when used under medical control, they have little approved medical use. LSD, peyote, psilocybin, and ecstasy are all classified as Schedule 1 drugs.

Colorado law subdivides drug misdemeanors into two tiers: level 1 to level 2.

Level 1 drug misdemeanors are the most serious category of Colorado drug misdemeanors. Common examples of level 1 drug misdemeanors in Colorado include:

  • The Colorado crime of unlawful drug possession (of schedule III, IV or V drugs, or up to 4 grams of schedule I or II drugs, or drugs listed in part 2 or Article 18 of Title 18, not including flunitrazepam or ketamine.)
  • The Colorado crime of marijuana possession (more than 6 oz. or more than 3 oz. of marijuana concentrate)
  • The Colorado crime of attempting to commit a level 4 drug felony

The minimum penalty for level 1 drug misdemeanors is: 6 months in jail and/or $500 in fines And the maximum penalty for level 1 drug misdemeanors is: 18 months in jail and/or $5,000 in fines Starting March 1, 2020, the punishment for unlawful possession is: Probation of up to 2 years; Possibly 180 days in jail; and Up to $1,000.


In limited circumstances, Colorado has authorized the legalization of marijuana possession for those aged 21 and up. In Colorado, however, possessing more than 28 grams / one ounce of marijuana – or any quantity of marijuana by people under 21 other than medical marijuana – is a felony. Possession of marijuana is also prohibited on federally owned land in Colorado, and is subject to stricter regulations: National Parks, airports, courthouses, the Veteran’s Administration, HUD housing, and post offices are all examples of federal property.

The safest way to obtain psychedelics in Colorado

Pursuing criminal charges for the possession and cultivation of psilocybin mushrooms for personal use has become the lowest priority for the Denver authorities although the distribution of psilocybin is still not allowed. You may want to consider growing your own medicine. Psilocybe spores are legal in Colorado.



Harm reduction

Other medication

Many people who want to try magic mushrooms are still on medication and want to know if it’s possible to mix their medication with psychedelics. While psilocybin has been shown to effectively treat depression and a variety of other mental health conditions, some antidepressant drugs can interact with the substance in a dangerous or undesirable way.

Interactions between Psilocybin and other medication

Antidepressant drugs may block the therapeutic effects of Psilocybin. If you are on antidepressants, you need to ask your health provider to help you stop taking them before considering psychedelics. SSRIs function by preventing excess serotonin from being cleared from the brain, resulting in a temporary increase in serotonin levels. Although it has been hypothesized that this may contribute to serotonin syndrome in extreme situations, such risks can be reduced with appropriate guidance and medical supervision.  Most common SSRIs are:

  • Citalopram (Celexa, Cipramil)
  • Escitalopram (Lexapro, Cipralex)
  • Fluoxetine (Prozac, Sarafem)
  • Fluvoxamine (Luvox, Faverin)
  • Paroxetine (Paxil, Seroxat)
  • Sertraline (Zoloft, Lustral)

Health conditions that psilocybin may worsen

At first, the findings revealed that people who had used psychedelic drugs were more likely to have mental health issues. However, the researchers took into account a variety of variables that may have influenced the findings, including the participants’ age, gender, and their experience with any highly stressful life event, all of which may influence the likelihood of mental health problems. When those factors were taken into account, the researchers found that people who had used psychedelics were no more likely to develop mental health problems than those who hadn’t used the drugs.

However, it’s not advisable to use psychedelics if you or your family members had psychotic symptoms.

Mushrooms in non-clinical settings are typically eaten orally, either as dried caps and stems or steeped in hot water and drunk as a tea, with a typical dose of 1-2.5 grams, though potency varies depending on the volume. Fresh mushrooms are usually less active than dried mushrooms. There is virtually no chance of accidental deadly overdose with psilocybin mushrooms.

Johns Hopkins study found Psilocybin dosage sweet spot for positive and lasting effects

Researchers found that as higher doses of chemically pure psilocybin were administered, the recorded positive effects increased, but there was also a sharp rise in the negative effects at the very highest dose, which was perhaps unsurprising. At the maximum dose (30 mg/70 kg, p.o. – meaning “per oral” or “by mouth”), 78 percent of the volunteers recorded one of the top five most spiritually important events of their lives, but those experiencing anxiety, stress, and fear episodes increased sixfold, resulting in about a third of those in the study showing signs of psychological distress.

By contrast, only one of the volunteers receiving the second-highest dose (20mg/70 kg, p.o.) reported having negative issues, and all benefited from positive experiences, although with less intensity than at the highest dose. Critically, even the lowest amount used in the study resulted in notable and long-lasting positive changes in the attitudes, behavior, overall satisfaction and spiritual beliefs of the subjects during the period of study. These changes were also noticed by family members and friends.

Psilocybe cubensis

The concentrations of psilocin and psilocybin, as determined by high-performance liquid chromatography, are in the range of 0.14–0.42% and 0.37–1.30% (dry weight) in the whole mushroom, 0.17–0.78%, and 0.44–1.35% in the cap, and 0.09 and 0.30%/0.05–1.27% in the stem, respectively.

Psychedelics – assisted psychotherapy in Colorado

With this psilocybin vote, Denver is breaking new ground. Colorado and the Mile High City are poised to anchor an ongoing psychedelic revival, where once maligned psychoactive substances are being championed as therapeutic treatments for illnesses including anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder, thanks to voter-approved legislation forcing police to relax enforcement of laws around psilocybin mushrooms.